Chemical priming of hypoxia responses via PLANT CYSTEINE OXIDASE inhibition improves flooding tolerance
Clicks: 1
ID: 321001
2026
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
0.0
/100
1 views
0 readers
AI Quality Assessment
Not analyzed
Readership in this journal
Ranked #486 of 502 articles by views in Plant physiology and biochemistry : PPB
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 502 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Abstract Extreme flooding driven by climate change demands strategies to enhance plant tolerance to low-oxygen stress. We investigated the ability of bioactive compounds to chemically prime plants for flooding events. A high-throughput chemical genetic screen of 2237 bioactive molecules was performed using an Arabidopsis thaliana luciferase-based reporter line driven by the ALCOHOL DEHYDROGENASE promoter, a hypoxia-inducible gene involved in anaerobic metabolism. The screen identified chlorquinaldol, an 8-hydroxyquinoline derivative, as a potent inducer of hypoxia responses. Chlorquinaldol inhibits the activity of PLANT CYSTEINE OXIDASES (PCOs), which are crucial oxygen-sensing enzymes in plants, resulting in the stabilization of the ETHYLENE RESPONSE FACTOR type VII and activation of hypoxia-responsive transcription under normoxic conditions. Plants pre-treated with chlorquinaldol showed enhanced tolerance to waterlogging and submergence, indicating that chemical priming of hypoxia responses improves plant tolerance to flooding. This study demonstrates that chemical inhibition of PCOs is an effective strategy for priming hypoxia responses and improving flooding tolerance in plants.
| Reference Key |
openalex_W7168254739
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Francesco Fioriti, Rocco Pierpaolo Germano, Noemi La Monaca, Dona M Gunawardana, Rebecca Latter, Antonietta Santaniello, Emily Flashman, Paolo Maria Triozzi, Pierdomenico Perata |
| Journal | Plant physiology and biochemistry : PPB |
| Year | 2026 |
| DOI |
10.1093/plphys/kiag505
|
| URL | |
| Keywords | Keywords not found |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.