A consecutive 2-year increase in the modified health assessment questionnaire score is associated with subsequent fractures in patients with rheumatoid arthritis

Clicks: 38
ID: 320175
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #15 of 49 articles by views in modern rheumatology

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
OBJECTIVES: Rheumatoid arthritis (RA) is a well-recognised risk factor for fractures. However, short-term fracture risk factors remain unclear. This study aimed to elucidate factors useful for short-term fracture prevention. METHODS: Patients were enrolled in the National Database of Rheumatic Diseases in Japan (2002-2020) were analysed. Modifiable risk factors included changes in disease activity, modified health assessment questionnaire (mHAQ) scores and oral glucocorticoid usage. RESULTS: Of the 37,466 patients with RA enrolled, 1655 experienced a first fracture. Sex, age, disease duration, disease activity, mHAQ score and glucocorticoid usage significantly differed between patients with and without fractures. Among 734 with 4-year pre-fracture data, mHAQ scores gradually increased over consecutive years before the fracture. When classified into four groups according to mHAQ changes over 2 consecutive years, patients with continuous increases had significantly higher fracture incidence (2.13%) than those with increases only in years 1-2 (1.43%), only in years 2-3 (1.59%) or with no increase across 2 consecutive years). CONCLUSIONS: A consecutive 2-year increase in mHAQ score is associated with an increased risk of subsequent fracture in patients with RA, offering valuable insight for targeted fracture prevention strategies.
Reference Key
openalex_W7167645465 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Yumi Arai, Naohiro Izawa, Shigeto Tohma, Toshihiro Matsui, Yuho Kadono
Are you one of these authors? Claim your profile
Journal modern rheumatology
Year 2026
DOI
10.1093/mr/roag058
URL
https://doi.org/10.1093/mr/roag058
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.