Eosinophilic solid and cystic renal cell carcinoma: a case report of a young Ghanaian female

Abstract Eosinophilic solid and cystic renal cell carcinoma (ESCRCC) is a rare entity recently included in the world health organization classification of kidney tumors. Due to its indolent behavior and insufficient characterization, it is often misdiagnosed. This report describes the case of a 28-year-old Ghanaian female who presented with a 1-year history of a gradually enlarging, initially painless right flank mass detected on self-examination, without any hematuria. A contrast-enhanced abdomino-pelvic computerized tomography scan demonstrated a well-defined, heterogeneously enhancing mixed solid and cystic lesion measuring 9.9 × 7.3 × 9.0 cm arising from the interpolar region of the right kidney. She had open radical right nephrectomy. Post-operative pathological immunohistochemical staining diagnosed ESCRCC. She is currently doing well after 8 months with no concern for metastasis. Initial misdiagnosis could negatively impact patient outcome and therefore underscores the need for early and definitive diagnosis of ESCRCC.