Chromatin dynamics and cellular energy homeostasis
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ID: 319216
2026
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Abstract
Metabolism is a complex consortium of chemical reactions, consuming and releasing energy. In addition, cellular respiration is a pivotal catabolic process of nutrients using oxygen to generate ATP. Dynamics of chromatin structure are fundamental to genomic events in all cellular processes. Therefore, chromatin consumes robust cellular energy formed in metabolism. To regulate cellular processes, chromatin functions and metabolism need to be tightly coordinated in response to environmental changes including nutrition availability. Indeed, molecular oxygen directly impacts DNA and chromatin modification and influences cell fate. Herein, we review fundamentals of chromatin dynamics, nucleosome modifications, and roles of chromatin dynamics in spatiotemporal regulation of cellular energy homeostasis.
| Reference Key |
openalex_W7166850809
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|---|---|
| Authors | Tamaki Suganuma, Jerry L. Workman |
| Journal | The Journal of Biochemistry |
| Year | 2026 |
| DOI |
10.1093/jb/mvag051
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| URL | |
| Keywords | Keywords not found |
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