Evolutionary and Structural Analysis Reveals the Gradual Establishment and High Conservation of Auxin Pathways from Algae to Land Plants

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ID: 318931
2026
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Abstract
Abstract Ever since Went first characterized auxins in 1928, the evolutionary history of this phytohormone and its underlying pathway has remained a foundational question for the plant science community. In this study, we comprehensively traced the origin and diversification of auxin biosynthesis, metabolism, transport, and signaling pathways across plant lineages. Here, we proposed a model of how protein interactions involved in auxin signaling gradually became established over evolution, evaluated the evolutionary similarities and differences among these pathways, and found that these evolutionary patterns align closely with the mutational and selective landscapes observed in natural populations of Arabidopsis thaliana. Notably, auxin-related pathways exhibited generally low conservation in algae. However, in Klebsormidium nitens, genes responsive to auxin induction were generally enriched in various auxin-related pathways. To further identify and fill the gaps in the auxin pathway in Algae, we conducted a protein structural prediction and identified candidate proteins with highly conserved structures of TMK1, ABP1 and TIR1 auxin receptors between Algae and a higher evolutionary status plant such as A. thaliana.
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Authors Luyao Yu, Junyao Lu, Xifeng Yan, Xiaoxuan Li, Xi Zhang, Peter Marhavý, Petra Marhavá, B. Zhong, Guochen Qin, Zhaojun Ding
Journal Plant physiology and biochemistry : PPB
Year 2026
DOI
10.1093/plphys/kiag439
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