When Does Clostridioides difficile “Recur”? Reconcile Epidemiologic & Bedside Recurrent CDI definitions

Clicks: 1
ID: 317648
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal

Ranked #393 of 430 articles by views in The Journal of infectious diseases

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 430 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Recurrent Clostridioides difficile infection (CDI) is a clinical syndrome, a trial endpoint, and a surveillance construct. Epidemiologic and administrative datasets count repeat positive tests or coded episodes, but conflate colonization or test of cure with recurrence. Trials operationalize recurrent CDI with symptoms, testing, but have variable follow-up. Clinically, recurrent CDI requires response, and recurrent illness excluding post-infection bowel dysfunction and mimics. Relapse and reinfection remain difficult to distinguish without strain typing which is more relevant for research. We propose a pragmatic lens: explicitly name the definition used, match it to the decision, and adjudicate clinical recurrence before escalating therapy.
Reference Key
openalex_W7165010862 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Sahil Khanna, Paul Feuerstadt, J Allegretti, Darrell S Pardi
Journal The Journal of infectious diseases
Year 2026
DOI
10.1093/infdis/jiag307
URL
https://doi.org/10.1093/infdis/jiag307
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.