Approach to the Patient: Cases of Hormonal Management in Older Transgender and Gender Diverse Adults

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ID: 316999
2026
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Ranked #355 of 362 articles by views in the journal of clinical endocrinology & metabolism

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Abstract
As the general population continues to shift to an older demographic, more transgender and gender diverse (TGD) adults will seek out endocrinologists and other healthcare providers to help them navigate both initiation and continuation of gender-affirming hormone therapy (GAHT) concurrent with the potential development of age-associated diseases. The purpose of this Approach to the Patient article is a case-based approach to management considerations in older TGD adults in the settings of neurocognitive disorder, increased cardiovascular disease risk, prostate cancer, bone health and menopause. While evidence-based guidelines for these aging-related conditions do not exist specifically for TGD adults, clinical practice and data from studies in TGD and cisgender adults are discussed to support the approaches to these patient cases. Future research in these areas can inform best practices and clinical guidelines for care of older TGD adults.
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openalex_W7164367383 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Micol S. Rothman, Jason O. van Heesewijk, Danit Ariel, Sean J. Iwamoto
Journal the journal of clinical endocrinology & metabolism
Year 2026
DOI
10.1210/clinem/dgag231
URL
Keywords Keywords not found

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