A Case Report of Acute RV Failure in a Patient Undergoing Transesophageal Echocardiogram for Evaluation of Tricuspid Regurgitation
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ID: 316935
2026
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Abstract
Abstract Background Transesophageal echocardiography (TEE) is generally considered a low-risk procedure. However, in patients with severe tricuspid regurgitation (TR) complicated by right ventricular (RV) dysfunction and pulmonary hypertension (PH), standard procedural sedation can precipitate life-threatening hemodynamic collapse. Case Summary An 83-year-old woman with end-stage renal disease, severe PH (95 mmHg), and severe TR underwent a TEE. Shortly after induction with propofol and probe insertion, the patient developed profound systemic hypotension (56/30 mmHg). Real-time TEE imaging revealed acute, severe RV dilatation and a precipitous decline in systolic function. The procedure was immediately aborted, and the patient was stabilized with intravenous phenylephrine and ephedrine. She returned to her hemodynamic baseline within 20 minutes of procedure termination and probe removal. Discussion This case highlights the “triple hit” effect that places patients with RV failure at high risk during sedation: propofol-induced systemic vasodilation, the vagal response to probe insertion, and hypercapnia-induced increases in pulmonary vascular resistance (PVR). For this high-risk phenotype, a “slow and low” anesthetic titration, meticulous PVR management, and early consideration of RV-protective vasopressors are essential to prevent catastrophic RV-pulmonary uncoupling.
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| Authors | Mustafa Mohammed, Andrew Chou, S R Parikh, Alexandra Deporre, James McCord |
| Journal | European Heart Journal - Case Reports |
| Year | 2026 |
| DOI |
10.1093/ehjcr/ytag423
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| URL | |
| Keywords | Keywords not found |
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