Transcatheter edge-to-edge mitral repair with a nitinol device in cardiogenic shock on micro-axial flow-pump support: a case report

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ID: 316543
2026
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Abstract
Abstract Background Severe functional mitral valve regurgitation due to acute myocardial infarction in the setting of profound cardiogenic shock presents a challenging treatment scenario. Persistent mitral regurgitation despite successful myocardial revascularization requires a careful and effective treatment approach. Case summary A 54-year-old male was admitted to our cardiac arrest center due to severe cardiogenic shock. The patient underwent percutaneous coronary intervention with stenting of the left main coronary artery, left anterior descending and ostial left circumflex artery in the setting of a ST-elevation myocardial infarction. After successful revascularization cardiogenic shock persisted and advanced temporary mechanical circulatory support with extracorporeal membrane oxygenation and a micro-axial flow pump, a was required. Further diagnostic evaluation revealed severe functional mitral regurgitation despite sufficient left-ventricular unloading. We present a case in which temporary mechanical circulatory support stabilized the patient and mitral regurgitation was successfully eliminated using a transcatheter edge-to-edge repair flexible nitinol device. Discussion While mitral valve transcatheter edge-to-edge repair in cardiogenic shock on mechanical circulatory support is rare, it has shown feasibility and positive outcomes in limited reports. This is the first case using a nitinol edge-to-edge repair device in this context. Our report emphasizes the need for further discussion on device selection and comparative studies to optimize treatment in this high-risk group.
Reference Key
openalex_W7164011501 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Daniel Schwarzkopf, Hristian Hinkov, Chong Bin Lee, Christoph Klein, Axel Unbehaun
Journal European Heart Journal - Case Reports
Year 2026
DOI
10.1093/ehjcr/ytag420
URL
https://doi.org/10.1093/ehjcr/ytag420
Keywords Keywords not found

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