Tumor-field predominant bullous pemphigoid in a patient with metastatic melanoma

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ID: 316504
2026
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Abstract
Bullous pemphigoid (BP) has increasingly been reported in melanoma patients, particularly in association with modern oncologic therapies. We describe a case of BP strikingly confined to the cutaneous field harboring the primary melanoma and in-transit metastases following sequential immune checkpoint inhibition and BRAF/MEK targeted therapy. This tumor-field–restricted pattern highlights a possible spatial link between melanoma biology, local immune dysregulation, and BP pathogenesis.
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openalex_W7164061269 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Alessia Caligiure, Endrio Kaja, Alba Guglielmo, Arianna De Martino, Sebastiano Posenato, Lucia Mantovani, Aikaterini Kalpaktsoglou, Roberta Gafà, Massimo Guidoboni, Alessandro Borghi
Journal clinical and experimental dermatology
Year 2026
DOI
10.1093/ced/llag243
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