Acute Mitral Regurgitation After Transcatheter Tricuspid Valve Replacement – Case Report

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ID: 315822
2026
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Abstract
Abstract Background Transcatheter tricuspid valve replacement (TTVR) has emerged as a therapeutic option for patients with severe tricuspid regurgitation (TR) who are ineligible for surgery. Case Summary We report the first case of acute development and transient resolution of severe mitral regurgitation (MR) following TTVR device implantation. Baseline transthoracic echocardiography (TTE) showed torrential TR and mild to moderate MR. Immediately after TTVR-device implantation, transesophageal echocardiography (TOE) revealed severe MR. Over the following days, MR gradually improved, and TTE at discharge showed only mild to moderate MR. Discussion This case illustrates that abrupt elimination of TR can lead to acute worsening of MR, likely precipitated by an abrupt increase in left ventricular preload in the presence of diastolic dysfunction. In conclusion, caution is warranted in patients with pre-existing left ventricular dysfunction undergoing TTVR, as the procedure may exacerbate functional MR. Periprocedural volume unloading may help ameliorate the impact of acute hemodynamic changes.
Reference Key
openalex_W7163320108 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Barbara Rubinić, Carolina Göttsche Esperança Clara, M Ivannikova, Tanja K Rudolph, Johannes Kirchner
Journal European Heart Journal - Case Reports
Year 2026
DOI
10.1093/ehjcr/ytag391
URL
https://doi.org/10.1093/ehjcr/ytag391
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