Cone reconstruction for EBSTEIN anomaly: Effect on tricuspid valve growth and biventricular remodeling in children
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ID: 315030
2026
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Abstract
OBJECTIVES: This study aimed to evaluate the surgical outcomes of cone reconstruction (CR) in paediatric patients with Ebstein anomaly (EA). METHODS: We retrospectively reviewed seventeen paediatric patients (<18 years) with EA (Carpentier types A, B, and C in 3, 12, and 2, respectively) who underwent CR without prosthetic annuloplasty materials between January 2014 and December 2024. Clinical outcomes, including tricuspid valve (TV) and biventricular function and size, were evaluated using echocardiography and cardiac magnetic resonance imaging (CMR). RESULTS: The median age and body weight at surgery were 7.8 years and 21.2 kg, respectively. No operative mortality occurred; however, three patients required permanent pacemaker implantation before discharge. No late deaths, reoperations, or significant tricuspid regurgitation (TR, ≥moderate) or stenosis (mean pressure gradient ≥5 mmHg) occurred during the 8.2-year median follow-up. TR was significantly reduced postoperatively (odds ratio 1.34, 95% confidence interval: 1.10 to 1.64, p = 0.008) and remained stable without recurrence of significant TR during follow-up. The mean TV annulus z-score decreased significantly after CR (1.81 [1.19] preoperatively versus -1.74 [0.92] at discharge, mean difference: -3.55, 95% confidence interval: -4.30 to -2.80, p < 0.001) and remained within the normal range during follow-up (-1.74 [0.92] at discharge versus -1.61 [1.11] at the last follow-up, mean difference: 0.04, 95% confidence interval: -0.02 to 0.10, p = 0.207). Postoperative CMR demonstrated significantly reduced TR fraction and right heart volumetric parameters, except functional right ventricular end-systolic volume and pulmonary forward flow volume indices. Based on CMR, left ventricular end-diastolic (change 2.40, 95% confidence interval: 0.52 to 4.27, p = 0.014) and systolic (change 1.75, 95% confidence interval: 0.74 to 2.76, p = 0.002) volume indices significantly increased over time. CONCLUSIONS: Long-term outcomes after CR without prosthetic annuloplasty materials were favourable in paediatric patients with EA. CR can achieve durable reduction of TR with sustained TV growth, potentially facilitating biventricular reverse remodelling.
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| Reference Key |
openalex_W7162451266
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|---|---|
| Authors | J B Lee, Woong-Han Kim, Seung Min Baek, H W Kwon, S K Cho, Jae Gun Kwak, Yoon Seong Lee |
| Journal | Interdisciplinary CardioVascular and Thoracic Surgery |
| Year | 2026 |
| DOI |
10.1093/icvts/ivag156
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| URL | |
| Keywords | Keywords not found |
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