Saliva as a Non-Invasive Diagnostic for Ocular Sarcoidosis
Clicks: 1
ID: 314876
2026
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
0.0
/100
1 views
0 readers
AI Quality Assessment
Not analyzed
Readership in this journal
Ranked #80 of 88 articles by views in journal of leukocyte biology
Most read
Least read
Bar heights use a square-root scale.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Sarcoidosis (SRS) is a multi-organ granulomatous disorder that predominantly affects the eyes, lungs, and skin. Biopsy, the standard for a definitive SRS diagnosis, is often impractical for ocular sarcoidosis (OSRS) due to the delicate nature of the eye and risks associated with surgical procedures such as inflammation, infection, retinal detachment, and cataracts. OSRS is typically treated with steroids and immunosuppressive medications. However, because infectious uveitis exhibits a similar clinical presentation as OSRS, there is an incipient risk of inappropriate treatment without a definitive diagnosis. Failing to prescribe immunosuppressive medications to OSRS patients can lead to scarring and permanent blindness; conversely, prescribing this treatment to infectious uveitis patients risks exacerbating the infection and associated pathologies. Saliva is an emerging diagnostic biofluid which is easy to collect, cost-effective, and is well-tolerated by patients. Although saliva has been used to identify biomarkers for diseases like cancer and diabetes, its use in diagnosing ocular diseases remains limited. This review provides an overview of SRS and OSRS, the utility of saliva as a diagnostic, and a pilot experiment to test if saliva could be used for OSRS diagnosis.
| Reference Key |
openalex_W7162292208
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Priya Hegde, Clayton Sandel, Alexander Schmidt, Stacey Lee, Janine Preble, C Stephen Foster, Stephen Anesi, Shilpa Kodati, Dimitrios Karmichos, Darren J. Lee |
| Journal | journal of leukocyte biology |
| Year | 2026 |
| DOI |
10.1093/jleuko/qiag065
|
| URL | |
| Keywords | Keywords not found |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.