Trajectories of reproductive events from menarche to menopause: identifying patterns and differences by childhood maltreatment and socioeconomic position

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ID: 314864
2026
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Abstract
To identify unique trajectories of reproductive events across the life course and determine if childhood socioeconomic position (SEP) or childhood maltreatment, independently or jointly, are associated with trajectory membership. We used data from the Coronary Artery Risk Development in Young Adults (CARDIA) study (n=2,787). We fit group-based trajectory models for self-reported reproductive events (complicated/uncomplicated pregnancies, irregular menses, contraceptive use) to assign individuals to a reproductive events trajectory. We determined associations with self-reported childhood maltreatment and childhood SEP and their interactions using Poisson regression with robust standard errors controlling for baseline age and self-reported race (Black or White). We identified three trajectories (n1 = 1,039; n2=778; n3 = 970). Group 3 had the youngest age at first pregnancy (mean 20.3 years vs. 28.3 and 31.7 for Groups 2 and 1 respectively), highest parity, and lowest risk of complications. Individuals reporting childhood maltreatment and low SEP had 1.48 times the risk of belonging to Group 3 versus Group 2 (1.48 (1.28, 1.71) compared to those reporting neither. Childhood maltreatment and low childhood SEP were both associated with belonging to an earlier childbearing group.
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openalex_W7162310092 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Kaitlyn K. Stanhope, Audrey J Gaskins, Catherine Kim, Cora E. Lewis, Shakira F. Suglia, Erica P. Gunderson
Journal american journal of epidemiology
Year 2026
DOI
10.1093/aje/kwag113
URL
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