Bioactivity of two Turkish endemic Centaurea species, and their major constituents

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Abstract
The antioxidant activity, general toxicity and cytotoxicity of the methanol extracts of Centaurea urvillei subs. armata and C. mucronifera have been assessed, respectively, by the DPPH assay, the brine shrimp lethality and the MTT cytotoxicity assays. The reversed-phase HPLC analysis of the methanol extracts afforded two bioactive dibenzylbutyrolactone-type lignans, matairesinoside (1) and arctiin (2). The structures of these lignans were elucidated by comprehensive spectroscopic analyses as well as by the direct comparison of experimental data with respective literature data.
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shoeb0000bioactivityrevista Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Shoeb, Mohammad;MacManus, Stephen M.;Jaspars, Marcel;Kong-Thoo-Lin, Paul;Nahar, Lutfun;Celik, Sezgin;Sarker, Satyajit D.;
Journal revista brasileira de farmacognosia
Year 0000
DOI
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URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2007000200003&lng=en&tlng=en
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