Clinical course of cerebral hemorrhage in infective endocarditis: focus on microbleed and small-area hemorrhage

Clicks: 1
ID: 314558
2026
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal

Ranked #56 of 85 articles by views in Interdisciplinary CardioVascular and Thoracic Surgery

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Abstract
Abstract OBJECTIVES This study aimed to review the surgical details and postoperative outcomes of on-pump valve surgery for preoperative central nervous system complications, especially infective endocarditis (IE) with cerebral microbleeds and small cerebral Haemorrhage, in patients with acute IE. METHODS Between January 2015 and June 2024, we performed 54 surgeries for IE, with intracranial Haemorrhage occurring in 13 of the 30 patients with preoperative central nervous system complications. RESULTS Among the 13 patients with intracranial Haemorrhage, 11 had cerebral infarction, 6 had cerebral microbleed, 2 had small hemorrhages not meeting the definition of cerebral microbleed, and 5 had conventional Haemorrhage. The median time from bleeding to surgery was 1, 2 and 20 days for cerebral microbleeds, small hemorrhages, and conventional hemorrhages, respectively. The main valve procedures were double valve replacement (five patients), mitral valve replacement (six patients), and aortic valve replacement (two patients). Postoperative computed tomography (CT) showed worsening cerebral Haemorrhage in three patients (23.1%,95% CI 5.0–53.8%), including one with cerebral microbleed and two with small Haemorrhage. Two patients with small Haemorrhage required postoperative neurosurgical embolization (15.4%,95% CI 1.9–45.4%). Postoperative complications included in-hospital death in one patient with conventional Haemorrhage (7.7%,95% CI 0.2–36.0%), but no deaths due to central nervous system complications were observed. CONCLUSIONS In our cohort, over half of the patients with IE presented with central nervous system complications, with cerebral Haemorrhage accounting for 43%. Postoperative Haemorrhage worsened in all patients with small Haemorrhage who underwent early intervention. Although the prognostic impact was minimal, small hemorrhages that were not cerebral microbleeds had a high rate of exacerbations requiring neurosurgery and should be treated with caution.
Reference Key
openalex_W7161968104 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Yoshitaka Yamamoto, Masaki Ushijima, Ai Sakai, Yu Nosaka, Hiroki Nakabori, Hideyasu Ueda, Akira Murata, Kenji Iino
Journal Interdisciplinary CardioVascular and Thoracic Surgery
Year 2026
DOI
10.1093/icvts/ivag154
URL
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

No comments yet. Be the first to comment on this article.