Evolving conservation: The role of unconventional approaches to restore contemporary vertebrate populations and genomic biodiversity

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ID: 314519
2026
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Abstract
Conservation biology and restoration ecology are two essential yet distinct disciplines that address the growing challenge of biodiversity loss. Traditionally, these fields have relied on ecological principles and management practices aimed at protecting or reestablishing natural systems. The crisis is no longer just ecological; it is evolutionary and genomic. The accelerating pace of environmental change has outstripped the capacity of conventional approaches, creating a pressing need for innovative solutions. Biotechnology offers potentially transformative tools that can enhance the effectiveness and precision of both conservation and restoration efforts, especially for species where conventional conservation approaches have proven insufficient. Techniques such as genetic rescue, synthetic biology, and gene editing are increasingly being explored to address critical challenges such as invasive species control, genetic diversity loss, and habitat fragmentation to both invigorate endangered species and restore historical biodiversity. Despite its promise, the integration of biotechnology into conservation and restoration has raised ethical, ecological, and regulatory concerns. These include ecological unpredictability and public resistance to genetic interventions in wild populations. This perspective examines the current landscape of biotechnological applications in conservation and restoration, highlighting successful case studies, ongoing controversies, and optimism for further progress. We argue that thoughtful, transparent integration of biotechnology that is grounded in ecological knowledge and stakeholder engagement can reconcile the goals of conservation and restoration. As ecosystems face mounting pressures, biotech-enabled strategies may prove essential for fostering resilience and ensuring long-term ecological sustainability.
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openalex_W7162041058 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Bridgett M Von Holdt, Matt James, Stephen J. Gaughran, Alexandra L. DeCandia, Klaus‐Peter Koepfli, Dan Flores, Nucharin Songsasen, Kristin E. Brzeski, Evelyn L. Jensen
Journal journal of heredity
Year 2026
DOI
10.1093/jhered/esag040
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