This paper explores the concept of gratitude (shukr) in Islam and its psychological implications for enhancing human well-being. Gratitude, emphasized repeatedly in the Qur’an and Hadith, is framed as both an act of worship and a cognitive-emotional state that fosters positivity, resilience, and contentment. The study highlights how Islamic teachings encourage gratitude not only towards Allah but also towards people, strengthening social bonds and community harmony. Psychological research affirms that practicing gratitude is associated with reduced stress, improved mood, and greater life satisfaction. By analyzing Qur’anic verses, Prophetic traditions, and modern psychological frameworks, this paper demonstrates that shukr serves as a protective factor against negative emotions while nurturing optimism, emotional regulation, and spiritual connectedness. It concludes that gratitude, as conceptualized in Islam, offers a holistic pathway to mental, emotional, and spiritual well-being.