Chronic Cardiorenal Syndrome: Review: Part 3

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ID: 311588
2025
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Abstract
heart failure (CHF) induces gradual kidney damage, leading to chronic cardiorenal syndrome (cCRS). This condition is linked with an increase in morbidity and death rate. The commonest cause of cCRS is CHF with a low ejection fraction. CHF causes alteration of hemodynamic variables, such as low cardiac output, neuroendocrine activation, venous congestion, and chronic inflammatory reaction activation. cCRS is a chronic condition that leads to hemodynamic and chronic heart and kidney fibrosis. There are no specific biomarkers to diagnose the cCRS. There is a debate regarding the causal relationship between CHF and kidney function impairment in cCRS. The debate has centered on the efficacy, safety, and costeffectiveness of the currently available therapeutic options, such as diuretics and angiotensinconverting enzyme inhibitors. Full, clear scientific recommendations for the prevention and treatment of cCRS are required.
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habas2026chronic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Elmukhtar Habas, Aml Habas, Amnna Rayani, Ala Habas, Khaled Alarbi, Eshrak Habas, Mohamed Baghi, Mohammad Babikir, Abdelrahaman Hamad, Almehdi Errayes
Journal Yemen Journal of Medicine
Year 2025
DOI
10.63475/yjm.v4i3.0223
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Keywords Keywords not found

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