Intravenous dexamethasone-induced perineal pain in children

Dexamethasone is one of the most commonly used corticosteroids in pediatric practice, especially for allergies and various types of airway inflammation. Since the 1980s, there have been many reports of the occurrence of short-lived, self-limiting, and unpleasant perineal pain in adults, particularly women, following intravenous administration [1,2]. In this letter, we describe two cases of young girls who suffered from severe anogenital pain that occurred immediately after starting the injection of intravenous dexamethasone