Molecular Dynamics Simulation Study of Denaturation of Protein Under the Influence of Electric Field

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ID: 310408
2023
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Ranked #124 of 409 articles by views in International Journal of Science and Social Science Research

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Abstract
The present study investigated the effect of static electric field on the structural changes in the Ubiquitin protein using molecular dynamics simulations. Structural transitions of Ubiquitin are observed under the influence of an electric field such that at a higher electric field, helix and sheets turn into coil and the protein gets stretched and unfolded. The RMSD variation with respect to time clearly shows that the larger the electric field strength, the more rapid structural transition is observed. Increased value of dipole moment for higher electric field supports the charge re-distribution and thus the unfolding of Ubiquitin under the influence of the electric field.
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imported_1768931363_696fc0237c982 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors M.S. Panchbhai
Journal International Journal of Science and Social Science Research
Year 2023
DOI
10.5281/zenodo.13380581
URL
Keywords Keywords not found

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