Metabolites Produced by Alkaliphiles with Potential Biotechnological Applications.

Alkaliphiles are a diverse group of relatively less known microorganisms living in alkaline environments. To thrive in alkaline environments, alkaliphiles require special adaptations. This adaptation may have evolved metabolites which can be useful for biotechnological processes or other applications. In fact, certain metabolites are found unique to alkaliphiles or are effectively produced by alkaliphiles. This probably aroused the interest in metabolites of alkaliphiles. During recent years, many alkaliphilic microbes have been isolated, especially in countries having alkaline environments, like soda lakes. Even if the number of such isolated alkaliphiles is large, their metabolites have not yet been extensively analyzed and exploited. This is expected to come in the years ahead. So far, the focus of interests in metabolites from alkaliphiles falls into categories such as organic acids, ingredients for foodstuffs and cosmetics, antibiotics, and substances which modify properties of other materials used in industry. This chapter deals with biotechnologically important metabolites of alkaliphiles including compatible solutes, biosurfactants, siderophores, carotenoids, exopolysaccharides, and antimicrobial agents. It also covers the promising potential of alkaliphiles as sources of bioplastic raw materials. Moreover, an overview of the patent literature related to alkaliphiles is highlighted. Graphical Abstract.