Molecular Analysis and Interpreting Molecular Data

This chapter focuses on molecular analysis and interpreting molecular data. It looks at the types of data generated from homogenate and intact cell and tissue preparations and considers how these could be analysed through qualitative, semi-quantitative, and quantitative methods. Moreover, the chapter explores bioinformatics as an answer to the interrogation of DNA and RNA target sequences, epigenetic changes, and DNA-protein relationships. It provides an overview of the application of telepathology, and image capture and analysis to achieve diagnosis without requiring microscopy. Finally, the chapter highlights the significance of developing sophisticated bioinformatics algorithms in an effort to correlate data from various sources with clinical pathology data in order to aid the diagnosis of disease and patient management.