Formulation and Assessment of Herbal Toothpaste utilizing extract from Pomegranates, Amla, Alum and Clove Oil

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ID: 309244
2024
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Abstract
The preparation and evaluation of a unique herbal toothpaste using extracts from clove oil (Eugenia caryophyllata), pomegranates (Punica granatum), amla (Phyllanthus emblica), and alum (potassium aluminumsulfate) are shown in this work. Pomegranate peel, amla fruit, alum, and clove oil were used in the formulation process to extract bioactive components, which were then included into a toothpaste base. The toothpaste was subjected to physicochemical characterisation in order to assess variables like stability, viscosity, and pH. Using standardized microbiological assays, the antibacterial activity of the herbal toothpaste was evaluated against common oral pathogens, such as Porphyromonasgingivalis and Streptococcus mutans. Additionally, in vitro and in vivo tests using animal models were used to examine the toothpaste's capacity to prevent plaque formation and lessen gingival irritation. The developed herbal toothpaste outperformed conventional toothpaste controls in terms of antibacterial effectiveness against tested microorganisms, according to the results. It also showed encouraging results in preventing the production of plaque and decreasing gingival irritation, suggesting that it could be a useful dental hygiene solution. Clove oil added to the herbal toothpaste formulation enhanced its analgesic and antibacterial qualities, balancing the effects of alum, amla, and pomegranate extracts. Eugenol, the main component of clove oil, has been demonstrated to have strong antibacterial action against dental pathogens and to relieve gingivitis and toothaches. The herbal toothpaste that has been created using extracts of pomegranates, amla, alum, and clove oil shows promise as a means of improving dental health. Utilizing these natural constituents' synergistic benefits, the toothpaste provides a secure and efficient substitute for traditional oral hygiene solutions. In order to confirm its effectiveness, safety, and long-term advantages for maintaining oral health, more clinical research is necessary.
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imported_1761930112_6904eb80aa920 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Baibhaw Kumar, Nimish Batra, Deepti Chauhan, Pooja Mehra
Journal International Journal of Pharmaceutical Drug Design (IJPDD)
Year 2024
DOI
10.62896/ijpdd.1.6.5
URL
https://ijpdd.org/index.php/files/article/view/130
Keywords Keywords not found

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