The Complication of Severe Malaria: Focus on Black Water Fever

Clicks: 41
ID: 309192
2025
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #6 of 153 articles by views in International Journal of Pharmaceutical Drug Design (IJPDD)

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 153 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Blackwater fever is a rare but severe complication of malaria, primarily caused by Plasmodium falciparum infection. It is characterized by the sudden onset of intravascular hemolysis, hemoglobinuria (dark or blackcolored urine), fever, and often jaundice. The condition results from the massive destruction of red blood cells, often associated with repeated use of quinine-based antimalarial drugs and incomplete treatment of malaria. Clinical features may include severe anemia, renal failure, and circulatory shock, posing a high risk of mortality if left untreated. Advancements in diagnostic tools, such as polymerase chain reaction (PCR) for malaria detection and improved renal function monitoring, have facilitated early diagnosis. Management involves prompt antimalarial therapy, fluid resuscitation, and in severe cases, blood transfusion and renal replacement therapy. Despite its declining prevalence due to improved malaria control programs and the introduction of artemisinin-based therapies, blackwater fever remains a critical concern in endemic areas. This review highlights the pathophysiology, clinical presentation, and modern approaches to managing this lifethreatening condition
Reference Key
imported_1761926624_6904dde006d79 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Yadala Prapurnachandra
Journal International Journal of Pharmaceutical Drug Design (IJPDD)
Year 2025
DOI
DOI not found
URL
https://ijpdd.org/index.php/files/article/view/213
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.