Beyond The Surface: Insights Into Psoriasis Pathophysiology and Therapy

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ID: 309183
2025
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Ranked #49 of 153 articles by views in International Journal of Pharmaceutical Drug Design (IJPDD)

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Abstract
The autoimmune disease known as psoriasis affects 2-3 percent of all people worldwide while remaining as a continuous skin disorder. The clinical expressions from psoriasis adversely affect both physical health alongside mental wellness of patients. Pathogenesis arises via immune dysregulation that mostly affects keratinocyte proliferation through IL-23/Th17 axis activation. Genetic inheritances work together with environmental triggers as well as immune system responses to start and drive the development of diseases and progression. Medical professionals provide patients with mild psoriatic symptoms topical remedies yet systemic biologic drugs fight inflammatory cytokines in serious situations. A promising development emerges from JAK inhibitors and IL-23 antagonists which have become new therapeutic options. The study examines both the disease mechanism and medical approaches and new strategies for treating psoriasis.
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imported_1761926612_6904ddd4497c0 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Gupta Aman Suresh, Sunita Thakur*, Vishakha Jaiswal
Journal International Journal of Pharmaceutical Drug Design (IJPDD)
Year 2025
DOI
10.62896/ijpdd.2.4.4
URL
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