Qualitative and Quantitative Study of Phytochemicals and Antioxidant Activity of Ethanolic Extract of Notonia Grandiflora Leaves

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ID: 309149
2025
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Abstract
The present study aimed to evaluate the phytochemical composition and antioxidant activity of the ethanolic extract of Notonia grandiflora leaves. The extraction process yielded 12.5% ethanolic extract, indicating a high content of polar phytoconstituents. Preliminary phytochemical screening confirmed the presence of important bioactive compounds such as alkaloids, flavonoids, phenols, glycosides, saponins, tannins, and proteins. Quantitative analysis revealed that the extract contained 0.52 mg/100 mg of total flavonoids and 0.89 mg/100 mg of total phenols, which are known contributors to antioxidant activity. The antioxidant potential was assessed using the DPPH radical scavenging assay. The ethanolic extract showed dose-dependent inhibition of DPPH radicals with a maximum of 51.87% at 100 µg/ml, and an IC₅₀ value of 95.11 µg/ml compared to 18.14 µg/ml for the standard antioxidant, ascorbic acid. These findings suggest that Notonia grandiflora leaves are a rich source of antioxidant phytochemicals and may have potential applications in the development of natural antioxidant therapies.
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imported_1761926386_6904dcf259985 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Upendra Kumar*, Dr. Satkar Prasad, Dr. Sailesh Kumar Ghatuary
Journal International Journal of Pharmaceutical Drug Design (IJPDD)
Year 2025
DOI
10.62896/ijpdd.2.6.08
URL
https://ijpdd.org/index.php/files/article/view/298
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