The Lutropin/Choriogonadotropin Receptor, A 2002 Perspective

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ID: 306777
2002
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Abstract
Reproduction cannot take place without the proper functioning of the lutropin/choriogonadotropin receptor (LHR). When the LHR does not work properly, ovulation does not occur in females and Leydig cells do not develop normally in the male. Also, because the LHR is essential for sustaining the elevated levels of progesterone needed to maintain pregnancy during the first trimester, disruptions in the functions of the LHR during pregnancy have catastrophic consequences. As such, a full understanding of the biology of the LHR is essential to the survival of our species. In this review we summarize our current knowledge of the structure, functions, and regulation of this important receptor.
Reference Key
openalex_W2066964651 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Mario Ascoli, Francesca Fanelli, Deborah L. Segaloff
Journal endocrine reviews
Year 2002
DOI
10.1210/edrv.23.2.0462
URL
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