The Insulin-Related Ovarian Regulatory System in Health and Disease

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ID: 303750
1999
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Abstract
I. Introduction II. Insulin and Insulin Receptor A. Structures of insulin and insulin receptor B. Presence of insulin and insulin receptor in the ovary C. Insulin action and the ovary D. Summary III. IGFs and Their Receptors A. IGF peptides and receptors B. Expression of IGFs and IGF receptors in the ovary C. Role of IGFs in ovulatory function and steroidogenesis D. Summary IV. IGF-Binding Proteins (IGFBPs) and Proteases A. Structural relationships among IGFBPs B. IGFBP expression in the ovary C. IGFBP proteases in the ovary D. IGFBP actions in the ovary E. Role of IGFBPs in follicular development and atresia F. Summary V. Polycystic Ovary Syndrome (PCOS) A. Clinical features B. Theories of pathogenesis C. Insulin resistance in PCOS D. Alterations of IGFs and IGFBPs in PCOS E. Summary VI. The Insulin-Related Ovarian Regulatory System: Implications for Therapy A. Treatment of PCOS B. Therapeutic use of IGF-I and IGF-II C. Use of GH in ovulation induction VII. Summary and Conclusions
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openalex_W2077815106 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Leonid Poretsky, Nicholas A. Cataldo, Zev Rosenwaks, Linda C. Giudice
Journal endocrine reviews
Year 1999
DOI
10.1210/edrv.20.4.0374
URL
https://academic.oup.com/edrv/article-pdf/20/4/535/8864791/edrv0535.pdf
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