THE NUMBER OF HETEROZYGOUS NUCLEOTIDE SITES MAINTAINED IN A FINITE POPULATION DUE TO STEADY FLUX OF MUTATIONS

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ID: 302234
1969
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Abstract
N natural populations, it is expected that there is a constant supply of muta-I tions in each generation.These mutations may have different persistence depending on their fitnesses, but collectively, they constitute the ultimate source of genetic variability in the populations.Since the maintenance of genetic variability is an important subject of study in population genetics, it may be worthwhile to investigate, using various models, the effect of mutation on the genetic variability.For example, KIMURA and CROW (1964) studied the number of alleles maintained in a finite population, assuming that each mutant is an allele not preexisting in the population.
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openalex_W2147476214 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Makoto Kimura
Journal current genetics
Year 1969
DOI
10.1093/genetics/61.4.893
URL
https://doi.org/10.1093/genetics/61.4.893
Keywords Keywords not found

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