Nanocarrier-based systems for targeted and site specific therapeutic delivery.

Clicks: 181
ID: 29943
2019
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Ranked #29 of 51 articles by views in Advanced drug delivery reviews

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Abstract
Systemic drug delivery methods such as oral or parenteral administration of free drugs possess relatively low treatment efficiency and marked adverse side effects. The use of nanoparticles for drug delivery in most cases substantially enhances drug efficacy, improves pharmacokinetics and drug release and limits their side effects. However, further enhancement in drug efficacy and significant limitation of adverse side effects can be achieved by specific targeting of nanocarrier-based delivery systems especially in combination with local administration. The present review describes major advantages and limitations of organic and inorganic nanocarriers or living cell-based drug and nucleic acid delivery systems. Among these, different nanoparticles, supramolecular gels, therapeutic cells as living drug carriers etc. have emerged as a new frontier in modern medicine.
Reference Key
majumder2019nanocarrierbasedadvanced Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Majumder, Joydeb;Taratula, Oleh;Minko, Tamara;
Journal Advanced drug delivery reviews
Year 2019
DOI
S0169-409X(19)30121-8
URL
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