Estimation of Bacterial Densities by Means of the "Most Probable Number"

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ID: 298631
1950
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Abstract
THIS PAPER attempts to give a simple account of the concept of the most probable number (m.p.n.) of organisms in the dilution method. The concept is quite old, going back to McCrady (4) in 1915, and has been discussed by various writers from time to time, so that little of what I shall present is new. In addition, some advice is given on the planning of dilution series. The dilution method is a means for estimating, without any direct count, the density of organisms in a liquid. It is used principally for obtaining bacterial densities in water and milk. The method consists in taking samples from the liquid, incubating each sample in a suitable culture medium, and observing whether any growth of the organism has taken place. The estimation of density is based on an ingenious application of the theory of probability to certain assumptions. For a biologist, it is more important to be clear about these assumptions than about the details of the mathematics, which are rather intricate.
Reference Key
openalex_W2587508995 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors William G. Cochran
Journal biometrics
Year 1950
DOI
10.2307/3001491
URL
https://doi.org/10.2307/3001491
Keywords Keywords not found

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