Time series regression studies in environmental epidemiology

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ID: 298627
2013
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Abstract
Time series regression studies have been widely used in environmental epidemiology, notably in investigating the short-term associations between exposures such as air pollution, weather variables or pollen, and health outcomes such as mortality, myocardial infarction or disease-specific hospital admissions. Typically, for both exposure and outcome, data are available at regular time intervals (e.g. daily pollution levels and daily mortality counts) and the aim is to explore short-term associations between them. In this article, we describe the general features of time series data, and we outline the analysis process, beginning with descriptive analysis, then focusing on issues in time series regression that differ from other regression methods: modelling short-term fluctuations in the presence of seasonal and long-term patterns, dealing with time varying confounding factors and modelling delayed ('lagged') associations between exposure and outcome. We finish with advice on model checking and sensitivity analysis, and some common extensions to the basic model.
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openalex_W2115112857 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Krishnan Bhaskaran, Antonio Gasparrini, Shakoor Hajat, Liam Smeeth, Ben Armstrong
Journal International Journal of Epidemiology
Year 2013
DOI
10.1093/ije/dyt092
URL
Keywords Keywords not found

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