Covariance Analysis of Censored Survival Data
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ID: 291393
1974
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Abstract
The use of regression models for making covariance adjustments in the comparsion of survival curves is illustrated by application to a clinical trial of maintenance therapy for childhood leukemia. Three models are considered: the log linear exponential (Glasser [1967]); Cox's [1972] nonparametric generalization of this; and the linear exponential (Feigl and Zelen [1965]). Age and white blood count at diagnosis are both shown to be important for prognosis; adjustment for the latter variable has marked effects on the treatment comparisons. Both advantages and disadvantages with the regression approach are noted.
| Reference Key |
openalex_W2171720857
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|---|---|
| Authors | N. E. Breslow |
| Journal | biometrics |
| Year | 1974 |
| DOI |
10.2307/2529620
|
| URL | |
| Keywords | Keywords not found |
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