The roles of gut microbiota and circadian rhythm in the cardiovascular protective effects of polyphenols.

Clicks: 415
ID: 28650
2019
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Abstract
Polyphenols are secondary metabolites of plants that have been widely interested in for their health benefits as antioxidant. In the last decade, a large number of clinical trials and epidemiological studies have shown that long-term consumption of polyphenol-rich diet protects against chronic diseases such as cancers and cardiovascular diseases. Current cardiovascular researches have also suggested an important role of gut microbiota and circadian rhythm in the pathogenesis metabolic and cardiovascular diseases. It is known that polyphenols can modulate the composition of core gut microbiota and interact with circadian clock. In the present article, we summarize recent findings, review the molecular mechanisms and the potential of polyphenol as a dietary supplement for regulating gut microbiota and circadian rhythm for the prevention of cardiovascular diseases, and discuss future research directions.
Reference Key
man2019thebritish Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Man, Andy W C;Xia, Ning;Daiber, Andreas;Li, Huige;
Journal british journal of pharmacology
Year 2019
DOI
10.1111/bph.14850
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