Sphingosomes: Advancements and Emerging Applications in Advanced Drug Delivery Systems

Clicks: 77
ID: 283882
2025
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Article Quality & Performance Metrics
Overall Quality
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Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment 🥈 High Quality
79.0 /100
Academic Rigor 78.0%
Novelty 70.0%
Clarity 85.0%
Key Strengths
  • Addresses a relevant and important topic in drug delivery.
  • Provides a comprehensive overview of sphingosomes.
  • Highlights potential applications in various therapeutic areas.
Areas for Improvement
  • Limited information on specific experimental methodologies.
  • Lack of detailed results or data analysis in the abstract.
  • Author diversity could be improved.
AI Recommendations

The article should provide more detailed information on the experimental methodologies used to evaluate sphingosomes. Including specific results and data analysis would strengthen the findings. Addressing potential limitations and challenges associated with sphingosome-based drug delivery systems would also enhance the article.

Enhanced v2.0 Analysis NISO/DORA Compliant
NISO/DORA Compliant
Research Integrity
Trending Topic
High Impact
🔥 Hot Topic
Topic Trend
2025 Relevance
Relevance
90%
Importance
85%
Authorship
Collaborative
Authors
6
Diversity
60%
Research Integrity
COPE Standards
Integrity
80%
Innovation
73%
Interdisciplinary Value
🔀 Cross-disciplinary
72%
Practical Impact Potential
Real-world Applications
80%
Enhanced Evaluation v2.0: Following NISO RP-25-2016, DORA 2025, and COPE assessment standards with 13 quality dimensions.
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Ranked #5 of 9 articles by views in Current Pharmaceutical Research

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Abstract
In a variety of different scientific fields, vesicular systems have proven to be very effective carrier systems. Sphingosomes are bilayered vesicles having a fully enclosed aqueous membrane lipid bilayer made primarily sphingolipid, natural or synthetic. The instability, in vivo circulation duration, and cancer loading efficacy in cancer therapy are important limitations of the vesicle system (liposomes, niosomes) that are addressed by sphingosomes. The information was acquired by searching for Sphingosomes in the Scopus and Google Scholar databases. In clinical contexts, Chemotherapy, biological macromolecules, and diagnostics are delivered via sphingosomes. Due to their size and content, sphingosomes can take several forms. The report suggests that sphingosomes are a potential vesicular drug delivery system that may transport pharmaceutical substances for a variety of purposes.
Reference Key
imported_1760439580_68ee2d1ce7d92 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Prashant Das, Dinesh Kumar, Vrinda Gupta, Sonia Gupta, Rajni Tanwar, Kavita Behmani
Journal Current Pharmaceutical Research
Year 2025
DOI
10.63785/
URL
https://cpr.org.in/index.php/files/article/view/134
Keywords
Sphingosomes Drug Delivery Systems Vesicular Systems Lipid Bilayers Sphingolipids Cancer Therapy Pharmaceutical Substances Chemotherapy

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