Targeted HPTLC Profile, Quantification of Flavonoids and Phenolic Acids, and Antimicrobial Activity of Dodonaea angustifolia (L.f.) Leaves and Flowers

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ID: 281533
2023
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Abstract
In East Africa, Dodonaea angustifolia (L.f.) is a well-known medicinal herb. Its leaf is primarily studied in light of its ethnobotanical use. In terms of phytochemistry and biological activity, its flower is not studied. In a prior study, our team looked into phytochemical screening, antioxidant activity, and total phenolic levels. This study aims to compare the profiles and biological activities of the leaf and flower samples of D. angustifolia and to present therapeutic alternatives. The leaf and flower sample powders were extracted with methanol using ultrasound-assisted extraction (UAE). HPTLC profile was obtained using CAMAG—HPTLC equipped with VisionCATS software. Antimicrobial agar well diffusion assay and minimum inhibition concentration (MIC) were determined. The leaf and flower extracts of D. angustifolia showed antibacterial activity with a MIC value of 20 µg/mL against Enterococcus faecalis and Listeria monocytogenes. Similarly, 40 µg/mL was found to be effective against Aspergillus flavus. D. angustifolia flower is a rich source of flavonoids and phenolic acids. Because of its antibacterial properties and profile, which are almost the same, the flower is emerging as a viable option for medicinal alternatives.
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tessema2023targeted Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors F. Tessema; Y. H. Gonfa; Tilahun Belayneh Asfaw; Mesfin Getachew Tadesse; Tigist Getachew Tadesse; A. Bachheti; M. Alshaharni; Pankaj Kumar; Vinod Kumar; I. Širić; S. Abou Fayssal; K. Chaubey; R. K. Bachheti
Journal molecules
Year 2023
DOI
10.3390/molecules28062870
URL
Keywords Keywords not found

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