Premature ovarian insufficiency and infertility.

Clicks: 153
ID: 280877
2023
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Abstract
Premature ovarian insufficiency (POI) is the loss of ovarian function before the age of 40 years and can be spontaneous or iatrogenic. It is an important cause of infertility, and the diagnosis should be considered in any woman presenting with oligo/amenorrhoea, even in the absence of menopausal symptoms suchas hot flushes.The aim of this article is to provide an overview of the diagnosis of POI and its management with respect to infertility.Diagnostic criteria for POI are follicle-stimulating hormone levels >25 IU/L on two occasions at least one month apart following 4-6 months of oligo/amenorrhoea, with exclusion of secondary causes of amenorrhoea. Approximately 5% of women will have a spontaneous pregnancy after a POI diagnosis; however, most women with POI will require a donor oocyte/embryo for pregnancy. Some women may elect to adopt or live childfree. Fertility preservation should be considered for those at risk of POI.
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dhanushi-fernando2023prematureaustralian Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Dhanushi Fernando, Waduge;Vincent, Amanda;Magraith, Karen;
Journal Australian journal of general practice
Year 2023
DOI
10.31128/AJGP-08-22-6531
URL
Keywords
infertility adoption coping strategies Psychological Health couple’ s dyadic adjustment repeated treatment failures

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