Abnormal conduction-induced cardiomyopathy: a poorly explored entity.

Clicks: 166
ID: 280523
2024
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Ranked #5 of 330 articles by views in European heart journal supplements : journal of the European Society of Cardiology

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Abstract
A dyssynchronous biventricular activation, which can be determined by left bundle branch block, chronic right ventricular pacing, frequent premature ventricular complexes, or pre-excitation, can cause a global abnormal contractility, thus leading to systolic dysfunction and left ventricular remodelling in a unique nosological entities: abnormal conduction-induced cardiomyopathies. In this clinical scenario, the mainstay therapy is eliminating or improving LV dyssynchrony, removing the trigger. This usually ensures the improvement and even recovery of cardiac geometry and left ventricular function, especially in the absence of genetic background. A multidisciplinary approach, integrating advanced multimodal imaging, is essential for the systematic aetiological definition and the subsequent evaluation and aetiology-guided therapies of patients and their families. This review aims to describe mechanisms, prevalence, risk factors, and diagnostic and therapeutic approach to the various abnormal conduction-induced cardiomyopathies, starting from reasonable certainties and then analysing the grey areas requiring further studies.
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lalario2024abnormaleuropean Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Lalario, Andrea;Rossi, Maddalena;Allegro, Valentina;Gagno, Giulia;Perotto, Maria;De Luca, Antonio;Merlo, Marco;Sanna, Giuseppe Damiano;Sinagra, Gianfranco;
Journal European heart journal supplements : journal of the European Society of Cardiology
Year 2024
DOI
10.1093/eurheartjsupp/suae028
URL
Keywords
genetics cardiomyopathies cardiac conduction disorders dyssynchronopathy

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