A Rare Presentation of Acute Kidney Injury in Diffuse Large B-Cell Lymphoma: A Case Report.

Clicks: 139
ID: 277482
2023
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Abstract
Acute kidney injury from bilateral renal infiltration is rare in diffuse large B-cell lymphoma (DLBCL). We present the case of a 45-year-old woman with a three-month history of night sweats, weight loss, fever, and fatigue. Clinical evaluation revealed anemia, edema, cervical lymphadenopathy, and elevated blood pressure. Initial lab results indicated severe kidney injury, initially suspected to be chronic kidney disease, later ruled out. Radiological assessments confirmed mediastinal lymphadenopathy. A cervical lymph node biopsy led to a diagnosis of DLBCL. Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy improved renal function and hematological parameters. Subsequent staging CT confirmed lymphadenopathy. Close monitoring revealed a complete return to normal renal function after one month. Further follow-up was missed. This case emphasizes diagnostic complexities and the value of a multidisciplinary approach in managing complex clinical presentations.
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saleh2023acureus Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Saleh, Mahnosh;Salih, Noman;Kakakhel, Musa;Ullah, Izhar;Siraj, Hamza;Tariq, Muhammad Naveed;Ahmad, Kamran;
Journal Cureus
Year 2023
DOI
e45642
URL
Keywords
anemia chronic kidney disease (ckd) acute kidney injury (aki) lymphadenopathy cervical lymph node biopsy diagnostic complexities diffuse large b-cell lymphoma (dlbcl) mediastinal lymphadenopathy r-chop chemotherapy renal infiltration

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