A Serine-Substituted P450 Catalyzes Highly Efficient Carbene Transfer to Olefins In Vivo
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2013
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Abstract
Genetically encoded catalysts for non-natural chemical reactions will open new routes to sustainable production of chemicals. We designed a unique serine-heme ligated cytochrome “P411” that catalyzes efficient and selective carbene transfers ...
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| Reference Key |
brustad2013naturea
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|---|---|
| Authors | Pedro S. Coelho, Z. Jane Wang, Maraia E. Ener, Stefanie A. Baril, Arvind A. Kannan, Frances H. Arnold, Eric M. Brustad;Pedro S. Coelho;Z. Jane Wang;Maraia E. Ener;Stefanie A. Baril;Arvind A. Kannan;Frances H. Arnold;Eric M. Brustad; |
| Journal | Nature Chemical Biology |
| Year | 2013 |
| DOI |
10.1038/nchembio.1278
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| URL | |
| Keywords |
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