PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer

Clicks: 149
ID: 274468
2006
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Abstract
Prostate cancer (PrCa) is characterized by progression from an androgen-dependent phenotype to one that is inevitably androgen independent (AI) and lethal. Recent evidence strongly suggests that the phosphatidylinositol-3-kinase/Akt (PI3K/Akt) and androgen receptor (AR) signalling pathways provide p …
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Authors Mulholland DJ;Dedhar S;Wu H;Nelson CC;;
Journal Oncogene
Year 2006
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