Regulation of Wnt/beta-catenin signaling by protein kinases
Clicks: 311
ID: 274453
2010
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Abstract
The Wnt/beta-catenin signaling pathway plays essential roles during development and adult tissue homeostasis. Inappropriate activation of the pathway can result in a variety of malignancies. Protein kinases have emerged as key regulators at multiple steps of the Wnt pathway. In this review, we prese …
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| Reference Key |
em2010developmentalregulation
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|---|---|
| Authors | Verheyen EM;Gottardi CJ;; |
| Journal | Developmental dynamics : an official publication of the American Association of Anatomists |
| Year | 2010 |
| DOI |
DOI not found
|
| URL | |
| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
pubmed abstract
nih
national institutes of health
national library of medicine
models
research support
non-u.s. gov't
N.I.H.
Extramural
biological
embryonic development / physiology*
phosphorylation
signal transduction / physiology*
beta catenin / metabolism*
repressor proteins / metabolism
wnt proteins / metabolism*
homeostasis / physiology*
gene expression regulation / physiology*
protein kinases / metabolism*
pmid:19623618
pmc3173947
doi:10.1002/dvdy.22019
esther m verheyen
cara j gottardi
axin protein
|
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