Regulation of Wnt/beta-catenin signaling by protein kinases

Clicks: 208
ID: 274453
2010
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Abstract
The Wnt/beta-catenin signaling pathway plays essential roles during development and adult tissue homeostasis. Inappropriate activation of the pathway can result in a variety of malignancies. Protein kinases have emerged as key regulators at multiple steps of the Wnt pathway. In this review, we prese …
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Authors Verheyen EM;Gottardi CJ;;
Journal Developmental dynamics : an official publication of the American Association of Anatomists
Year 2010
DOI
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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19623618
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE review pubmed abstract nih national institutes of health national library of medicine models research support non-u.s. gov't N.I.H. Extramural biological embryonic development / physiology* phosphorylation signal transduction / physiology* beta catenin / metabolism* repressor proteins / metabolism wnt proteins / metabolism* homeostasis / physiology* gene expression regulation / physiology* protein kinases / metabolism* pmid:19623618 pmc3173947 doi:10.1002/dvdy.22019 esther m verheyen cara j gottardi axin protein

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