Effects of in vitro hypoxia and lowered pH on potassium fluxes and energy metabolism in rat brain synaptosomes
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ID: 274223
1981
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Abstract
Synaptosomes isolated on isosmotic Ficoll density gradients are an effective model for some aspects of neuronal function. They maintain metabolic energy levels ([ATP]/[ADP] [Pi]) and transplasma membrane electrical potentials very similar to those of neurons in the intact brain. The concentration of …
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| Authors | Pastuszko A;Wilson DF;Erecińska M;Silver IA;; |
| Journal | Journal of Neurochemistry |
| Year | 1981 |
| DOI |
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| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
male
P.H.S.
Rats
Anaerobiosis
sodium / metabolism
hydrogen-ion concentration
energy metabolism*
calcium / metabolism
brain / metabolism*
adenosine triphosphate / metabolism
brain / ultrastructure
potassium / metabolism*
ouabain / pharmacology
oxygen / metabolism*
synaptosomes / metabolism*
adenosine diphosphate / metabolism
pmid:7463041
doi:10.1111/j.1471-4159.1981.tb02385.x
a pastuszko
d f wilson
i a silver
pentobarbital
synaptosomes / drug effects
veratridine / pharmacology
|
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