HSC70-JNK-BAG3 complex is critical for cardiomyocyte protection of BAG3 through its PXXP and BAG structural domains

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2021
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Abstract
Notwithstanding previous studies have proved the anti-apoptotic effect of Bcl-2 associated athanogene3 (BAG3) in myocardium, the structural domains PXXP and BAG responsible for its protection are not reformed. Since BAG3 in cardiomyocytes is a new target for inhibiting apoptosis induced by hypoxia/r …
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Authors Zhao LL;Gu JN;Zhu XF;Hu Y;Cao H;Yao N;Sang H;Guo BB;Wang YH;Qian HY;Zhu WZ;;
Journal Frontiers in bioscience (Landmark edition)
Year 2021
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