Regulation of leptin promoter function by Sp1, C/EBP, and a novel factor

Clicks: 323
ID: 274135
1998
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Abstract
Leptin is a hormone produced in adipose cells that regulates energy expenditure, food intake, and adiposity. To understand leptin's transcriptional regulation, we are studying its promoter. Four conserved and functional regions were identified. Mutations in the C/EBP and TATA motifs each caused an a …
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mm1998endocrinologyregulation Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Mason MM;He Y;Chen H;Quon MJ;Reitman M;;
Journal endocrinology
Year 1998
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/9492033
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't Adipocytes / metabolism Rats genetic* CCAAT-Enhancer-Binding Proteins Receptors Base Sequence Molecular Sequence Data DNA-Binding Proteins / physiology* Nuclear Proteins / physiology* Promoter Regions proteins / genetics* hela cells binding sites transcription factors / physiology cytoplasmic and nuclear / physiology sterol regulatory element binding protein 1 point mutation leptin sp1 transcription factor / physiology* pmid:9492033 doi:10.1210/endo.139.3.5792 m m mason y he m reitman zucker

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