A novel p34(cdc2)-binding and activating protein that is necessary and sufficient to trigger G(2)/M progression in Xenopus oocytes

Clicks: 281
ID: 274011
1999
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Abstract
The activation of maturation-promoting factor (MPF) is required for G(2)/M progression in eukaryotic cells. Xenopus oocytes are arrested in G(2) and are induced to enter M phase of meiosis by progesterone stimulation. This process is known as meiotic maturation and requires the translation of specif …
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Authors Ferby I;Blazquez M;Palmer A;Eritja R;Nebreda AR;;
Journal genes & development
Year 1999
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/10465793
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Molecular animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't amino acid sequence cell line DNA Base Sequence Molecular Sequence Data complementary cloning rabbits cell cycle proteins / genetics cell cycle proteins / metabolism* oocytes / drug effects progesterone / pharmacology xenopus proteins* xenopus oocytes / cytology enzyme activation cdc2 protein kinase / metabolism* mitosis* cycloheximide / pharmacology cyclin b / metabolism maturation-promoting factor / metabolism pmid:10465793 pmc316955 doi:10.1101/gad.13.16.2177 i ferby m blazquez a r nebreda g2 phase*

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