Novel next-generation sequencing-based methodologies to characterize the mutational consequences of (prenatal) chemotherapy exposure in noncancerous tissue

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ID: 273982
2021
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Ranked #2 of 2 articles by views in current opinion in oncology

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Abstract
Results of the latest investigations give valuable insights into the genome-wide genotoxicity profile of frequently applied chemotherapies, with most of these drugs being associated with a signature of random base substitutions and small indels. Though these findings still might be limited to extrap …
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Authors Struys I;Lenaerts L;Thienpont B;Amant F;;
Journal current opinion in oncology
Year 2021
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