Integration of regulatory networks by NKX3-1 promotes androgen-dependent prostate cancer survival

Clicks: 372
ID: 273773
2012
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #7 of 18 articles by views in molecular and cellular biology

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
The NKX3-1 gene is a homeobox gene required for prostate tumor progression, but how it functions is unclear. Here, using chromatin immunoprecipitation coupled to massively parallel sequencing (ChIP-seq) we showed that NKX3-1 colocalizes with the androgen receptor (AR) across the prostate cancer geno …
Reference Key
py2012molecularintegration Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Tan PY;Chang CW;Chng KR;Wansa KD;Sung WK;Cheung E;;
Journal molecular and cellular biology
Year 2012
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/22083957
Keywords
Tumor National Center for Biotechnology Information NCBI NLM MEDLINE genetic gene expression regulation humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't male cell line neoplastic* Receptors Promoter Regions transcription factors / genetics* transcription factors / metabolism prostatic neoplasms / genetics* protein binding gene regulatory networks* transcriptional activation androgens / metabolism cell survival androgen / metabolism prostatic neoplasms / metabolism prostatic neoplasms / pathology chromatin immunoprecipitation prostate / metabolism prostate / pathology homeodomain proteins / metabolism transcription factors / analysis homeodomain proteins / genetics* androgen / analysis pmid:22083957 pmc3255774 doi:10.1128/mcb.05958-11 peck yean tan cheng wei chang edwin cheung hepatocyte nuclear factor 3-alpha / metabolism homeodomain proteins / analysis androgen / genetics* rab3 gtp-binding proteins / genetics

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.