The hyperphagic effect of ghrelin is inhibited in mice by a diet high in fat
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ID: 273726
2010
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Abstract
This is the first report that diets high in fat inhibit the hyperphagic effect of ghrelin; these findings indicate that features of the diet are important determinants of ghrelin's function. This information is important for the development of anti-obesity drugs that target ghrelin signaling.
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| Authors | Gardiner JV;Campbell D;Patterson M;Kent A;Ghatei MA;Bloom SR;Bewick GA;; |
| Journal | gastroenterology |
| Year | 2010 |
| DOI |
DOI not found
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| URL | |
| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
Inbred C57BL
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
male
motor activity
dietary fats / administration & dosage*
energy intake
energy metabolism
inbred cba
insulin resistance
pmid:20178795
doi:10.1053/j.gastro.2010.02.012
james v gardiner
daniel campbell
gavin a bewick
ghrelin / pharmacology*
hyperphagia / chemically induced
hyperphagia / prevention & control*
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